Transmission of Virus
All types of Dengue Fever are transmitted by mosquitoes to humans through the bite of female mosquitos from the Aedes genus. The virus usually enters the female mosquito as it feeds on a person who is a carrier of this particular virus. When the mosquito is infected by the virus, the virus will be capable of spreading throughout the mosquito's life until its death. The average human infected with the Dengue virus will carry it for 4 to 16 days. During this period of time, the person can attain sudden fevers accompanied with amplified common cold symptoms. The virus can only be spread from the female Aedes Mosquito, and therefore, it is impossible for humans to spread the virus by themselves.("All about Dengue")
The virus itself infects through a typical viral infection mechanism. The virus injects its RNA genome into the rough endoplasmic reticulum (R. E. R.) of a cell. It will then proceed to produce a polyprotein chain using the cell's own DNA/mRNA translation mechanisms. This polyprotein will then be used in further RNA synthesis, which, in turn will produce further polyproteins. Eventually the mechanism will have produced enough polyproteins to synthesise another virus. These immature viruses head out of the endoplasmic reticulum through a process known as exocytosis, and exit the cell. During this process, the virus will mature and leave the infected cell, allowing further infection of other cells. (Dengue Virus Life Cycle Youtube VTI SWL 04. Youtube)
The virus itself infects through a typical viral infection mechanism. The virus injects its RNA genome into the rough endoplasmic reticulum (R. E. R.) of a cell. It will then proceed to produce a polyprotein chain using the cell's own DNA/mRNA translation mechanisms. This polyprotein will then be used in further RNA synthesis, which, in turn will produce further polyproteins. Eventually the mechanism will have produced enough polyproteins to synthesise another virus. These immature viruses head out of the endoplasmic reticulum through a process known as exocytosis, and exit the cell. During this process, the virus will mature and leave the infected cell, allowing further infection of other cells. (Dengue Virus Life Cycle Youtube VTI SWL 04. Youtube)